The cast of Scream 6 is full of great actors, both familiar faces from the previous movies and newcomers joining the ensemble, all playing characters who could secretly be a Ghostface killer. After successfully revitalizing the franchise with 2022’s “requel,” simply тιтled Scream, Matt Bettinelli-Olpin and Tyler Gillett got right back in the director’s chairs for the next movie. Scream 6 (officially тιтled Scream VI) leaves the town of Woodsboro behind for the first time and takes the action to the streets of New York City, where the characters are terrorized by yet another serial killer in a Ghostface mask.

Due to a salary dispute, this is the first film in the Scream franchise not to feature Neve Campbell as Sidney Prescott. But Scream 6 brings back plenty of other familiar characters. The cast includes appearances by recent additions to the ensemble from the 2022 requel, like Melissa Barrera and Jenna Ortega, as well as actors from earlier Scream films, like Courteney Cox, Hayden Panettiere, and, of course, Roger L. Jackson as the over-the-phone voice of Ghostface. The Scream 6 cast is one of the series’ biggest to date.

Actor	Character
Melissa Barrera	Sam Carpenter
Jenna Ortega	Tara Carpenter
Jasmin Savoy Brown	Mindy Meeks-Martin
Mason Gooding	Chad Meeks-Martin
Courteney Cox	Gale Weathers
Hayden Panettiere	Kirby Reed

Melissa Barrera As Sam Carpenter

Birthdate: July 4, 1990

Character: Melissa Barrera reprises her role from the previous Scream film as Sam Carpenter, the daughter of original Ghostface killer Billy Loomis. A final girl to her core, Sam is the spiritual successor of Sidney. Similar to Sidney, she was someone who was able to stand up and fight Ghostface and walk away from the situation alive, making it seem that she is replacing the original lead, even with Sidney possibly making her return in Scream 7.

Actor: Melissa Barrera got her start with roles in telenovelas like Siempre tuya Acapulco and Tanto amor. She went on to play the supporting role of Vanessa in the movie adaptation of In the Heights and the lead role of Liv Rivera in the Netflix series Keep Breathing. Barrera’s work in Keep Breathing and the Scream franchise earned her the тιтle of “scream queen.” Most recently, she appeared in the horror movie Abigail, allowing her to continue her career as a horror movie leading lady.

Jenna Ortega As Tara Carpenter

Birthdate: September 27, 2002

Character: Jenna Ortega reprises her role as Tara Carpenter, Sam’s half-sister who survived a Ghostface attack in the previous movie. Tara was a teenager when she first appeared in Scream 5 and survived that movie’s murders along with her sister. This means that she was back and ready to move on in Scream 6, although she is now attending college. She had a nice ending here, though, as she survived alongside her sister and chose to get therapy and help, which is more than many past characters attempted.

Actor: Ortega got her breakthrough playing young Jane in The CW’s Jane the Virgin and Harley Diaz in the Disney Channel’s Stuck in the Middle. In 2022, in addition to the Scream requel, Ortega starred as Lorraine Day in Ti West’s old-school slasher X and as the тιтular protagonist in the hugely popular Addams Family spin-off Wednesday on Netflix, for which she received Golden Globe and Emmy nominations. These three projects earned Ortega a place in the “scream queen” canon alongside Barrera.

Jasmin Savoy Brown As Mindy Meeks-Martin

Birthdate: March 21, 1994

Character: Jasmin Savoy Brown reprises her role from the last Scream movie as Mindy Meeks-Martin, Chad’s twin sister and the niece of horror buff Randy Meeks from the first two Scream films. Mindy famously shares her uncle’s love of horror cinema. Like her brother, she was one of the key teens helping everyone survive as the Ghostface killer continued to hunt them down. She is also another survivor, and she is currently filming Scream 7 as one of the returning characters.

Actor: Brown is best known for playing Evangeline Murphy in HBO’s dystopian drama The Leftovers, Allison Adams in ABC’s legal drama For the People, and a young Taissa Turner in Showtime’s psychological thriller Yellowjackets. She also provided the voice and motion capture for Phin Mason, also known as the Tinkerer, in the video game Spider-Man: Miles Morales.

Mason Gooding As Chad Meeks-Martin

Birthdate: November 14, 1996

Character: Mason Gooding returns in the role of Chad Meeks-Martin, Randy’s nephew and Mindy’s twin brother. Unlike Mindy, Chad doesn’t have a lot in common with Randy. Where Randy was a film geek with a love of horror, Chad is an athlete and a popular kid at his school. However, he is also someone who is smart and protective of his friends and his sister. He seemingly died in Scream VI, but it turned out he survived and he will return in Scream 7.

Actor: The son of actor Cuba Gooding, Jr., Gooding made his movie debut with the role of Nick Howland alongside Beanie Feldstein and Kaitlyn Dever in Olivia Wilde’s directorial debut, coming-of-age high school comedy Booksmart. He played the recurring role of Parker Jones on the HBO sports dramedy series Ballers and the starring role of Andrew Spencer in Hulu’s Love, Simon streaming spin-off Love, Victor.

Courteney Cox As Gale Weathers

Birthdate: June 15, 1964

Character: Courteney Cox, the only actor to appear on-screen in every single Scream movie, reprises her role as former news reporter Gale Weathers in Scream VI. Gale used the fame that followed her survival of every wave of Ghostface killings to launch a career as an author and talk show host. In the original movies, she was one of the only adults who was there to help the teens Ghostface was killing, and she ended up marrying Dewey, although he died in Scream 5.

Actor: Courteney Cox actually got her start appearing in a Bruce Springsteen music video, which led to early roles in the TV show Misfits of Science and the movie Ace Ventura: Pet Detective. Cox is best known for her role as Monica Geller on the classic sitcom Friends. She also played protagonist Jules Cobb in the series Cougar Town and appeared in movies like Masters of the Universe as Julie Winston, The Longest Yard as Lena, and Bedtime Stories as Wendy.

Hayden Panettiere As Kirby Reed

Birthdate: August 21, 1989

Character: Hayden Panettiere reprises her role from Scream 4 as Kirby Reed, who is now an FBI agent heading to New York to investigate a new string of Ghostface killings. In Scream 4, Kirby is a teenager who has to survive the killer, which convinced her to become a law enforcement officer to protect others like her. She was not in the fifth movie, so her return in the sixth one was a nice surprise for fans. Like Chad, it looked like Kirby died in the sixth movie, but she ended up surviving thanks to a bulletproof vest.

Actor: Panettiere is best known for her TV roles as Claire Bennet on NBC’s superhero series Heroes and Juliette Barnes on ABC and CMT’s musical drama series Nashville. The latter earned her two Golden Globe nominations. She starred as the тιтle characters in the movies I Love You, Beth Cooper and Amanda Knox: Murder on Trial in Italy. She has also done some voice work in video games, playing Kairi and Xion in the Kingdom Hearts series and Sam Giddings in Until Dawn.

Scream 6 Supporting Cast & Characters

The Rest Of The Scream 6 Characters

Henry Czerny as Dr. Christopher Stone: Sam’s therapist Dr. Christopher Stone is played by Henry Czerny. Czerny is best known as Eugene Kittridge from the Mission: Impossible franchise. He also played the starring role of the conniving, intelligent Conrad Grayson in ABC’s Revenge.

Dermot Mulroney as Detective Bailey: Detective Bailey, a cop on the case, is played by Dermot Mulroney. Mulroney is known for his roles as romantic comedy leads Michael O’Neal in My Best Friend’s Wedding and Nick Mercer in The Wedding Date. He also played more dramatic roles, such as Captain Martin Lee in Zodiac and Steve Heidebrecht in August: Osage County.

Liana Liberato as Quinn Bailey: Detective Bailey’s daughter Quinn is played by Liana Liberato. Liberato appeared as Avery Miller opposite Nicolas Cage and Nicole Kidman in the movie Trespᴀss and received two Daytime Emmy nominations for her starring role as McKenna Brady in the Hulu thriller series Light as a Feather. She also stars in the Peacock comedy-thriller series Based on a True Story as Tory Thompson.

Tony Revolori as Jason Carvey: Jason Carvey, whose first name is taken from the Friday the 13th killer, is played by Tony Revolori. Revolori is best known for his Wes Anderson roles, playing lobby boy Zero Moustafa in Wes Anderson’s The Grand Budapest H๏τel and Aide-de-Camp in Asteroid City. Revolori also famously played Peter Parker’s bully Flash Thompson in the MCU’s Spider-Man trilogy.

Jack Champion as Ethan Landry: Ethan Landry is played by Jack Champion in the cast of Scream 6. Champion is best known as Spider, the human child whom Jake and Neytiri adopted in Avatar: The Way of Water, a role he will reprise in Avatar 3 and Avatar 4.

Samara Weaving as Laura Crane: Laura Crane, whose last name is borrowed from Psycho, is played by Samara Weaving. Weaving first gained recognition with her role as Indi Walker on the soap opera Home and Away. She has since appeared in Ash vs. Evil ᴅᴇᴀᴅ as Heather, Three Billboards Outside Ebbing, Missouri as Penelope, Ready or Not as Grace Le Domas, and Colleen Moore in Babylon.

Devyn Nekoda as Anika Kayoko: Anika Kayoko is played by Devyn Nekoda. Nekoda previously played Riley in Ginny & Georgia season 1 and Arlene Takahashi in Degrᴀssi: The Next Generation season 14.

Josh Segarra as Danny Brackett: Danny Brackett, whose last name is taken from Halloween, is played by Josh Segarra. Segarra previously played Pug in She-Hulk: Attorney at Law, Stefanovic in Orange is the New Black, and the villainous Simon Morrison in Arrow season 5.

Roger L. Jackson as the voice of Ghostface: The creepy voice of the Ghostface killer in Scream VI is provided by Roger L. Jackson, who voiced the killer in all the previous Scream movies and in the Scream: Resurrection series. Jackson is also known for voicing Mojo Jojo on The Powerpuff Girls.